ea0025p121 | Diabetes, metabolism and cardiovascular | SFEBES2011
Gabr Mahmoud
, Hussein Abdel-aziz
, Sherif Iman
, Ali Sousou
, Mohamed Hoda
Background: Diabetes mellitus (DM) especially type II is a major health problem and diabetic nephropathy is the main cause of end stage renal disease (ESRD). Renal ischemia/reperfusion (I/R) injury is common in diabetic patients. Recent studies reported increased vulnerability of kidney to I/R injury in diabetic rats. Mechanisms behind this increased vulnerability not fully understood. The present study investigated the effect of acute ischemia for 45 min on proinflammatory cy...